::ALLIED INSTITUTION : COLLEGE OF PHARMACY : College of Pharmacy
COLLEGE      OF      PHARMACY
1.      HISTORY
2.      COURSES OFFERED
3.      ELIGIBILITY AND STUDENT INTAKE
4.      SELECTION PROCEDURE
5.      AFFILIATED UNIVERSITY
6.      ACADEMIC CALENDER
7.      UNIVERSITY EXAMINATION DETAILS
8.      DEPARTMENTS
               Pharmaceutics
               Pharmaceutical Chemistry
               Pharmacognosy
               Pharmacology
9.      PUBLICATIONS
10.  ALUMINI ASSOCIATION
11.  HIGHLIGHTS OF THE YEAR  2016
 
 
Pharmacy is the health profession that links health sciences with chemical sciences. It is concerned with the art and science of preparing drugs from natural and synthetic sources, materials for distribution and use in the prevention and treatment of disease.
 
Pharmacy embraces knowledge of identification, preservation, analysis and standardization of drugs of natural origin and others, synthesis of new drug molecules, manufacturing of various dosage form, quality control of drugs, clinical trials, mechanism of action, side effects, contraindications, indications of drugs and drug interactions. Pharmacy professionals therefore, are the experts on drugs and drug therapy contrary to the general perception that they merely compound and dispense medicines.
OUR VISION:
To achieve excellence in Pharmacy Education, Research and Services
      OUR MISSION: 
To produce Pharmacy Professionals of global standards by
Ø  Providing Quality education
Ø  Pioneering Research
Ø  Affording Pharmaceutical services
The future prospects for the Pharmacy graduates is bright and they find placements in various areas such as
  •  Pharmaceutical industries in the manufacturing and quality control divisions.
  • To be a part of basic research team to introduce new drug molecules in the market.
  • To be a part of the formulation research and development team of Pharma companies.
  • In the Drug Regulatory Affairs
  • As an academician
  • As part of clinical research organizations
  • To be a part of the health care, drug information, reviewing medicines for safety and efficacy.
  • As a registered Pharmacist to practice the profession of Pharmacy.
 
1. HISTORY
            Madras Medical College was the first institution in India to start Pharmacy Education and Training. A Certificate course with one year duration called “Chemist and Druggist Course” was started in the year 1897 to train personnel for dispensing of drugs. Consequent to the constitution of Pharmacy Council of India (PCI), the Chemist and Druggist Course was abolished and a new two year course “Diploma in Pharmacy” was commenced in the year 1955 with an annual intake of 60 students.
            Madras Medical College, the second in India and first institution in South India offered a two year Degree course “B.Sc. (Pharmacy)” affiliated to Madras University from the year 1939 with an annual intake of 10 students. This degree course was further modified as Bachelor of Pharmacy course in the year 1950 with a duration of three years which was later increased to four years.
            M. Sc. (Pharmacy) was started in 1956 with duration of two years but discontinued in 1975 and M.Pharmacy course in four specialties was started in the year 1995.
            A separate College of Pharmacy, Madras Medical College was established in the year 2008 and a post of Principal was also sanctioned. The College offers B.Pharmacy, M.Pharmacy and Ph.D. programme and has under its control three departments namely
  1. Department of Pharmaceutics
  2. Department of Pharmaceutical Chemistry
  3. Department of Pharmacognosy
 
2. COURSES OFFERED and DURATION
B.Pharm - 4 Years
M.Pharm- 2 Years
Ph.D       - 4 years (Part time).  Dept. of Pharmaceutical Chemistry is recognized by the Tamil Nadu Dr. M.G.R. Medical University   to do research leading to Ph.D.
 
3. ELIGIBILITY AND STUDENTS INTAKE
   B.PHARM
ELIGIBILITY
a)      Candidates belonging to all categories except scheduled Castes / scheduled Tribes
for admission to B. Pharm course must have obtained individual pass marks in Physics, Chemistry, Biology or Botany and Zoology or Mathematics both in theory and practical with a minimum of 35% marks. Not less than 50% aggregate marks in the above subjects is mandatory at the qualifying examination (academic stream)  after a period of 12 years of study i.e.10 + 2 pattern of education.
 
b)      Candidates belonging to scheduled castes / scheduled tribes must have obtained
Individual pass marks in Physics, Chemistry, Biology or Botany and Zoology (or) Mathematics both in Theory and Practical with a minimum of 35% marks and with not
less than 40% aggregate marks in the above subjects.
 
c)      A pass in English with a minimum of 35% marks is mandatory for all categories
for admission to the course.  (OR)
d)     Candidates qualified in the Diploma in Pharmacy examination conducted by the
Board of Examinations of the Government of Tamil Nadu or any other Board of any other
State recognized as equivalent thereto by the authority of this University.
 
INTAKE   
54 candidates per year for Ist - B.Pharm and 5 candidates for lateral entry to the second year B.Pharm.
M.PHARM
The College offers M.Pharm courses in         
Pharmaceutics
Pharmaceutical Chemistry
Pharmacognosy
Pharmacology
ELIGIBILITY
A pass in the B. Pharm Degree of The TN Dr.M.G.R. Medical University or any other University recognized as equivalent thereto by the authority of this University.
 
INTAKE       
            9 candidates in each specialty; Total: 36.
 
4. SELECTION PROCEDURE
Selection and admissions are made on merit basis for all categories of seats in B.Pharm and M.Pharm, through counselling, following the rule of reservation, choice of the candidates and availability of seats by the selection committee
 
5. AFFILIATED UNIVERSITY
            The college is affiliated to The Tamil Nadu Dr.M.G.R. Medical University
6. ACADEMIC CALENDER
            B.Pharm- September to August
M.Pharm- June to March
7. UNIVERSITY EXAMINATION DETAILS
B.Pharm - 1st August and 1st February
M.Pharm - 15th April and 15th October
 
 
 
 
 
DEPARTMENT OF PHARMACEUTICS
1.       HOME PAGE                                                    
WELCOME TO THE DEPARTMENT OF PHARMACEUTICS
            Drug development has become increasingly complex, time consuming and expensive. As a result there is an increased focus on making clinically established drugs perform better therapeutically in terms of efficacy, safety and improved patient compliance by designing novel and patentable technologies or delivery systems. This has led to a paradigm shift in drug delivery technologies from conventional dosage forms to controlled release and sophisticated delivery systems.
            These systems are based on the concepts of Biopharmaceutics and Pharmacokinetics driven by Pharmacodynamic activity and therapeutic needs. The department of pharmaceutics is one of the key departments of the Institute. It is equipped with state of the art facilities to undertake research in drug development, delivery and evaluation. The Academic Records of the Department of Pharmaceutics….
  • The Department of Pharmaceutics is recognized as Research centre leading to the award of Ph.D by the Tamil Nadu Dr. M.G.R. Medical University, Chennai.
  • Dept. of Pharmaceutics has Post Graduate course with 9 seats of annual intake.
  • The faculty members of the department are well qualified and experienced in the specialization. 
  • The department has expertise in research areas such as development and evaluation of newer formulations, targeted drug delivery system, pre-formulation and incompatibility studies.
2.      FACULTY DETAILS
TEACHING STAFF
            Professor & Head of Pharmaceutics – Prof. K.Elango, M.Pharm., (PhD.,)
            Associate Professor – Mr. K. Ramesh Kumar, M.Pharm.,
 Assistant Professor - Dr. N. Deattu, M.Pharm, Ph.D.,
         Dr. S. Daisy Chella Kumari, M.Pharm,Ph.D.,
                                             Dr. R. Devi Dayamanthi, M.Pharm,Ph.D.,
            NON- TEACHING STAFF
            Lab supervisor -                      R.Marthandam, M.Sc., DMLT.
            Technical staff -                      S. Manickam, DMLT      
3.  ACADEMICS                             
  B.Pharm
                     The subject of Pharmaceutics is taught from second year onwards.
  Second Year
Ø  Physical Pharmaceutics
Ø  Pharmacy Practice and Pathophysiology
Ø  Pharmaceutical Technology
Third Year
Ø  Pharmaceutical Dosage form and Cosmetic Technology
Ø  Hospital and Clinical Pharmacy
Ø  Pharmaceutical Jurisprudence &Pharmaceutical Business Management
  Final Year
Ø  Formulative Pharmacy and Biopharmaceutics
Ø  Pharmaceutical Biotechnology
             As a part of the curriculum the student also undertake a research project in the field of their interest.
 
 
M.Pharm
First year                                                                                                            
1. Industrial Pharmacy
2. Biopharmaceutics and Pharmacokinetics
3. Advances in Drug Delivery System
4. Modern Pharmaceutical Analytical Techniques (Common for all Branches)
  Second year.
Dissertation / research work
4. RESEARCH ACTIVITIES
Research in Pharmaceutics covers a broad spectrum of Pharmaceutical sciences ranging from the design, optimization, formulation and evaluation of drugs, through studies on methods of various drug delivery systems and on the fate of drugs in animals, to research on the clinical and sociological aspects of Pharmacy.
  • To build and increase the research base and capacity by providing research support to  post- doctoral fellows and graduate students at the participating institutions in newer techniques
  • To enhance science and technology knowledge to the staff and students in current trends
  • The Faculty of College of Pharmacy  is actively involving in collaboration program with various premier Institutions /Universities in India
    4.1 RESEARCH PROGRAM CARRIED OUT IN THE FOLLOWING AREA
v  Preformulation and Incompatibility Studies.
v  Formulation and Evaluation of Controlled Drug Delivery System
v  Process Validation of Formulated Products
v  Formulation and Evaluation of Novel Drug Delivery System
v  Design, Optimization and Characterization of Nanoparticles
    4.2. FUTURE PLANS OF THE DEPARTMENT
v  Targeted Drug Delivery System
v  Herbal Formulation and Standardization
v  Bioavailability and Bioequivalence studies
v  Pharmacokinetic and Pharmacodynamic Models
DEPARTMENT OF PHARMACEUTICAL CHEMISTRY
1. INFRASTRUCTURE AND FACILITIES
2. FACULTY DETAILS
3. ACADEMICS
4. RESEARCH ACTIVITIES
Research programs implemented in the Department
v  Future plans of the Department
v  Ongoing research work
 
DEPARTMENT OF PHARMACEUTICAL CHEMISTRY
The Dept. of Pharmaceutical Chemistry was established in 1960s and handles classes for I to IV B. Pharm, I and II M. Pharm. Apart from this, the dept. is approved for conduct of Ph.D. programs affiliated to the TN Dr. MGR Medical University. The Analytical laboratory of the department is approved by the Drugs Control Dept. of Tamil Nadu for analysis for drugs.
1. INFRASTRUCTURE AND FACILITIES
            There are well equipped and spacious laboratories to train UG and PG students with facilities for carrying out synthesis, molecular modeling, development and validation of analytical methods, extraction, isolation and identification of Phyto Pharmaceuticals.
The dept. is well equipped with three laboratories and one air-conditioned instrumentation laboratory with sophisticated instruments like UV/Visible spectrophotometer, High performance liquid chromatography (HPLC) etc.
 
2. FACULTY DETAILS
TEACHING STAFF
·          PRINCIPAL ,PROFESSOR AND HEAD
                        Dr. A. JERAD SURESH, M. Pharm, Ph.D., M.B.A.,
·         ASSISTANT PROFESSOR
                  Dr. P.G. Sunitha, M.Pharm, Ph.D.,
                  Dr. R. Priyadarsini, M. Pharm, Ph.D.,
                  Dr. M. Sathish, M. Pharm, Ph.D.,
                  Mrs. T. Saraswathy, M.Pharm., (Ph.D.,)
NON TEACHING STAFF
Laboratory Supervisors
                        Mr.D. Sivakumar M.Sc, DMLT.,
                        Mr.S. Baskar M.Sc, DMLT.,
                        Mrs.V. Mala B.Sc, DMLT.,
Technicians
                        Mrs.S. Maheswari DMLT.,
                        Mrs. V.Geetha M.Sc, DMLT.,
                        Mr.  K.N.Umapathy DMLT.,
                        Mr. B.Vijaya DMLT.,
3. ACADEMICS
The dept. handles seven subjects of Pharmaceutical Chemistry for B. Pharm and four subjects for M. Pharmacy as follows
B.PHARM
Ø  I B. Pharm
      Pharmaceutical Organic Chemistry
      Pharmaceutical Inorganic Chemistry
Ø  II B. Pharm
Advanced pharmaceutical Organic Chemistry
      Pharmaceutical Analysis and Physical Chemistry
Ø  III B. Pharm
      Medicinal Chemistry I
Ø  IV B. Pharm
      Medicinal Chemistry II
      Modern methods of Pharmaceutical Analysis
As a part of the curriculum the students also undertake a research project in a field of their interest (drug design, synthesis and characterization, analysis and Phyto Chemistry).
M.PHARM
Ø  I M. Pharm
      Modern Pharmaceutical Analytical Techniques (common to all branches of
         M. Pharm),
Advanced Organic Chemistry
Advanced Medicinal Chemistry
Natural Products of Medicinal Interest.
Ø  II M. Pharm
Dissertation/Research work
4. RESEARCH ACTIVITIES
    Research programs implemented in the Department
      Medicinal Chemistry
·         Synthesis, characterization and pharmacological screening of heterocyclic compounds.
·         Molecular modeling of drugs (QSAR analysis and docking)
·         Microwave assisted synthesis   
Analytical Chemistry
·         Development of methods of analysis of bulk drugs and formulation by UV, HPLC and HPTLC.
·         Validation of developed methods
·         Development of methods of analysis of biological fluids
      Chemistry of Natural Products (Phytochemicals)
·         Extraction of  plants
·         Isolation and characterization
·         Pharmacological screening of plant extracts and isolated compounds
Future plans of the Department
v  Self sustenance of the dept. by way of analysis of drugs and finished products for which a license has been obtained from the Drug control dept.
v  To bring about Institution-Industry interaction.   
v  To set up drug design lab with latest software.
v  To go in for eco friendly combinatorial synthesis
v  Development of newer analytical techniques for drugs not official
v  Study of impurity profile in drugs and pharmaceuticals
v  To achieve excellence in academic and research
 
DEPARTMENT OF PHARMACOGNOSY
 
1. INFRASTRUCTURE AND FACILITIES
2. FACULTY DETAILS
3. ACADEMICS
4. RESEARCH ACTIVITIES
Research program implemented in the Department
Future plans of the Department
Research studies conducted
Ongoing research work
 
 
This web portal of the Department of Pharmacognosy summarizes its current teaching, research and other activities. The motto of the Department of Pharmacognosy is not only to excel in the field of education but also in the field of research.
 
The word "Pharmacognosy" is derived from the two Greek words, "Pharmakon"or drug, and "gnosis" or knowledge. Pharmacognosy is the study of the structural, scientific and systematic studies of natural products from plant, marine and other life origins. It also deals with a variety of commercial and medicinal products such as pharmaceutical aids, allergenic extracts, herbicides and insecticides of natural origin.
 
Pharmacognosy occupies an important place in the pharmacy curriculum because it provides systematic and scientific validation of traditional medicines; it helps to develop lead molecules from natural source and to establish the pharmacological and biochemical roles of these molecules. Though the traditional medicine provides a gold mine for alleviating diseases there is a lacuna in the availability of standard preparation. Hence there is an urgent need to standardize these preparations, a major area of research. Pharmacognosy has undergone significant changes in recent years and today it is a highly interdisciplinary science. The subject seeks to bridge the gap between modern and traditional systems of medicine.
 
1. INFRASTRUCTURE AND FACILITIES
 
            There are well equipped and spacious laboratories to train UG and PG students with facilities for extraction, isolation and identification of Phyto Pharmaceuticals.
 
2. FACULTY DETAILS
 
TEACHING STAFF
 
·         PROFESSOR AND HEAD
 
Dr. R. Radha  M.Pharm, Ph.D.,
 
·         ASSISTANT PROFESSOR
Dr. P.Muthusamy, M.Pharm, Ph.D., B.L.,
Dr. R.Vijayabharathi M.Pharm, Ph.D.,
Dr. R. Vadivu, M.Pharm, Ph.D.,
Mrs. B.Kumudha Veni  M.Pharm.,
                                                      
TECHNICAL STAFF
           
                        Mrs. T.S.Lakshmi, DMLT.,   
                        Mrs.  M.Kumudhavalli  M.Sc., DMLT.,
 
3. ACADEMICS
 
  B.PHARM
 
The subject of Pharmacognosy at undergraduate level is included in the third
and final year. The subjects are   
III year
Ø  Pharmacognosy and Phytochemistry
      IV  year
Ø  Advanced Pharmacognosy                 
As a part of the curriculum the students also undertake a research project in the
field of their interest.
 
    M.PHARM           
 
     I M.Pharm
 
The curriculum includes the following subjects  
 
Ø  Pharmacognosy
Ø  Phytochemistry and Biotechnology
Ø  Chemistry of Natural products
 
 
   II M.PHARM
 
Dissertation / Research work
 
  1. RESEARCH ACTIVITIES
 
Scientific activities of the department cover the fields of all aspects of Pharmacognosy, Phytochemistry and Biological screening to enable us to focus attention on biologically active natural products. The core research activity of the department has always been the “exploration of Phyto medicines”. The rich flora of Tamil Nadu is an impetus for all the activities carried out in the department.
The current research in the department focuses on screening of medicinal plants with antidiabetic, hepatoprotective, leptospirocidal, antiulcer, anti arthritic, wound healing, analgesic, antioxidant, anti-inflammatory, antimicrobial, activities as well as standardization of herbal medicines.
Research programme implemented in the Department
v  Pharmacognostical and phytochemical studies of some selected medicinal plants
v  Screening of medicinal plants for their biologically active lead molecules              
v  Standardization protocols for the herbal drugs
v  Screening of herbal formulations for their biological activity
 
Future plans of the Department        
v  Expansion of the present research activities in the area of isolation, identification and characterization of biologically active constituents.
v  Production of biologically active constituents by tissue cultures.
v  Survey and documentation of medicinal plants available in Tamil Nadu
 
DEPARTMENT OF PHARMACOLOGY
 
(Attached to Institute of Pharmacology, Madras Medical College)
FACULTY DETAILS
 
TEACHING STAFF
 
·         PROFESSOR
 
Dr. N.Jayshree. Radha  M.Pharm, Ph.D.,
 
·         ASSISTANT PROFESSOR
Mrs. R.Indhumathi,M.Pharm, (Ph.D.,)
Mrs. M.Sakthi Abirami M.Pharm, (Ph.D.,)
Mr. V.Sivaraman M.Pharm,
 
 
 
9. PUBLICATIONS (2012-2015)
                                             
Name of the author       Article title      Journal Title
Dr. A.Jerad Suresh Discovery of Aurora Kinase: A inhibitors using virtual screening protocol J.Chem. Bio. Phy.Sci. Sec. B. 2012, Vol 2, No 3, 1333-1349
Dr. A.Jerad Suresh Determination of stability and degradation rate for combination containing Amoxycillin and Dicloxacillin in capsule dosage form Journal of Pharmaceutical research Vol 11 – No 1, January 2012; 1-5
Dr. A.Jerad Suresh Development of novel (1 –H) benzimidazole bearing pyridine –trione based MAO – A inhibitors: Synthesis, docking studies and antidepressant activity. Journal of Saudi Chemical Society (2012)  1.288
Dr. A.Jerad Suresh In Vitro studies of antioxidant and membrane stabilizing activity of 2 substituted 4, 5 – Diphenyl Imidazole derivatives American journal of Pharmtech research 2012; 2(4), 644 – 648
Dr. A.Jerad Suresh Antitumour activity of 5 (2E) – 1- (1H- benzimidazol – 2-yl) – 3- substituted phenylprop – 2 –en- 1 – ylidene) Pyrimidine – 2, 4, 6 )1H, 3H, 5H) – triones against Dalton’s ascetic lymphoma in mice. Medicinal Chemistry Research December 2012 ,1.612
Dr.V.Niraimathi Antileptospiral screening (in vitro) of some Aryl 1, 4 – dihydro pyridine derivatives. Indian journal of Pharmaceutics, Vol 3: Number 1, January – june 2012. Pp 15 – 18
Dr.V.Niraimathi Sensitive and selective colorimetric method for the determination of valsartan in Bulk and Oral Dosage Form IJPT 4 (1), 2012, pp.39-41
Dr.V.Niraimathi Selective and Sensitive Spectrophotometric determination of cinatapride and omeprazole in bulk and oral dosage form. IJPT 4 (1), 2012, pp.33 – 38
Dr.V.Niraimathi Quantification of cinitapride and Pantoprazole in Bulk and oral dosage form by visible spectrophotometric method. International journal of Pharmacy and Pharmaceutical Sciences. Vol 4, Issue 3: 2012
Dr.V.Niraimathi RP- HPLC Method development and validation for the estimation of cinitapride and omeprazole in solid oral dosage form International journal of Pharmacy and Pharmaceutical Sciences. Vol 4, Issue 4: 2012
Dr.V.Niraimathi Spectrophotometric methods for the estimation of valsartan in Bulk and oral Dosage form International journal of Pharmacy and Pharmaceutical Sciences. Vol 4, Issue 2: 2012
Dr.V.Niraimathi Visible spectroscopic methods for the estimation of cinitapride and pantoprazole in bulk and oral dosage form Research J. Pharm and Tech. 5(3): March 2012, p 440 – 444
Dr.V.Niraimathi Antimicrobial study (in vitro) of some Aryl 1,4 – (Dihydro Pyridine Derivatives) International journal of Pharmacy and Pharmaceutical Sciences. Vol 4, Issue 3: 2012, 212- 214
Dr.V.Niraimathi Spectrophotometric Methods for the estimation of Cinatapride and Omeprazole in Bulk and oral Dosage Asian Journal of Research chemistry, Feb 2012
Dr.R. Priyadharsini Docking, Synthesis, Characterization and evaluation of Novel CDK2 Inhibitors: Benzothiazole derivatives International journal of Pharmacy and Pharmaceutical Sciences. Vol 4, Issue 3: 2012, 574 – 584
Dr.R. Priyadharsini Docking studies, Synthesis, Charecterization of substituted Benzothiazoles as DHFR inhibitors and evalution of their antitubercular activities. Asian journal of research chemistry 5(9) September 2012
Dr.R. Priyadharsini Pharmacophore modeling and 3D – QSAR studies on substituted benzothiazole/benzimidazole analogues as DHFR inhibitors with antimycobacterial activity International journal of Pharma sciences and research, Vol 3, No : 8, Aug 2012
Dr.R. Priyadharsini Docking,synthesis, charecterisation of certain substituted Benzimidazole pyrimidines as potent DHFR inhibitorswith antimycobacterial activity. Journal of Pharmacy research 2012, 5(11), 5173 – 5177.
Dr.P.G.Sunitha Development and validation of UV spectrophotometric methods for the simultaneous determination of Emtricitabine and Tenofovir in combined dosage form Journal of Pharmacy research 2012, 5(2), 873 – 875
Dr.P.G.Sunitha Development and validation of spectrophotometric methods for the determination of efavirenz in pharmaceutical dosage form International journal of Pharma Research. July – December
Dr.P.G.Sunitha Development and validation of spectrophotometric methods for the quantification of efavirenz in tablets. Journal of Drug Delivery & Therapeutics; 2012, 2(6), 79 – 80
Dr. M.Sathish Antihyperlipidemic activity of various extracts from root of Clerodendrum phlomidis (Linn) in rat fed with Asian journal of Chemistry. Vol 24, No 8 (2012), 3541 – 3544
Dr. M.Sathish In vitro antioxidative activity of phenolic and flavonoid compounds extracted from root of Clerodendrum phlomidis (Linn) International journal of Pharmacy and Pharmaceutical sciences, Vol 4, issue 1, 2012
Prof..K. Elango Formulation and evaluation of dicyclomine hydrochloride Matrix Tablets for colon specific drug delivery. Research journal of Pharm tech and research 5(4) : April - 2012
Prof..K. Elango Formulation and evaluation of Bilayer tablets of losartan potassium for immediate release (IR) and Metformin hydrochloride for sustained release (SR) Journal of Pharmaceutics and Cosmetology. Vol 2: 8 (2012)
Prof..K. Elango Formulation and evaluation of colon targeted dicyclomine hydrochloride matrix tablets. The Indian Pharmacist, Volume X, No 10, April 2012.
 
Dr.S.Daisy Chellakumari
A Study of Aqueous film coating on Microcrystalline Hydroxy Apatite complex tablets International Journal of Pharmaceutical Sciences and Research;Vol 3,3(12),4851 – 4855, 2012.
 
Dr.S.Daisy Chellakumari
Formulation and Evaluation of Floating tablets of Ondansetron Hydrochloride. IJDDR; Vol 4, Issue 4, 265 – 274, 2012.
 
Dr.S.Daisy Chellakumari
Formulation and Evaluation of Colon targeted Dicyclomine Hydrochloride matrix tablets The Indian Pharmacist; Vol 10, 55-58. Apr 2012.
 
Dr.S.Daisy Chellakumari
Formulation and Evaluation of Controlled porosity osmotic tablets of Lornoxicam International Journal of Pharmaceutical Sciences and research, Vol 3(6), 1625-1631, 2012.
 
Dr.S.Daisy Chellakumari
Nose to brain direct delivery of Levodopa from Chitosan Nanoparticles – A Novel Approach. IJPI’s Journal of Pharmaceutics and Cosmetology; Vol 2:10, 2012.
Dr. N. Jayshree Development, standardization and Pharmacological evaluation of a polyherbal formulation to treat benign prostatic hyperplasia National conference on recent trends in Industrial Pharmacognosy
Dr. N. Jayshree Development, standardization and accelerated stability studies of a polyherbal formulation to treat Benign Prostatic hyperplasia Journal of Pharmacognosy and Herbal Formulations, Vol 2: 9 (2012)
Dr. R Radha Evaluation of Antiurolithiatic polyherbal formulation (capsule) Journal of Pharmacognosy and Herbal Formulation, Vol2: 9 (2012)
Dr P. Muthusamy Preliminary Phytochemical and in vitro antioxidant perspectives of the leaf extracts of Azima tetracantha  Lam. Family Salvadoraceae International journal of Pharma and Biosciences. Vol 3, Issue 1, Jan – Mar 2012
Dr. Vijayabharathi Determination of Phytoconstituents , Heavy metals and Inorganic elemental analysis of plant Vigna aconitifolia IJDT, Volume 3, Number 1, June 2012
Dr. A.Jerad Suresh Discovery of some novel imines of 2 amino, 5-thio,1,3, 4 thiadiazole as mucomembranous protector. Synthesis, antioxidant activity and in silico PASS approach. Journal of Saudi Chemical Society (2013)
Dr. A.Jerad Suresh Synthesis and PASS assisted in silico approach of some novel 2 substituted benzimidazole bearing a pyrimidine – 2,4 (trione) system as mucomembranous protector Journal of Pharmacy and Bioallied Sciences Vol 5, issue 1, January – March 2013
Dr. A.Jerad Suresh Synthesis and insilico design of some Novel Imines of 5 Amino- 1,3,4- Thiadiazole – 2 Thiol Linked to (1H – Benzimidazole – 2-yl)- 3 substituted phenyl Prop -2- ENES. Indian Journal of Heterocyclic chemistry Vol.22, April – June, 2013, PP. 337 – 340
Dr. A.Jerad Suresh Prediction of Binding energies/interactions between Diospyrin and different target proteins of Mycobacterium tuberculosis. Indo American Journal of Pharmaceutical Research, Vol 4 Issue 1, 2013
Dr. A.Jerad Suresh Simple UV Spectrophotometric Methods for the estimation of Isoniazid in Bulk and Pharmaceutical Dosage form. Indo American Journal of Pharmaceutical Research, Vol 4 Issue 1, 2013
Dr.V.Niraimathi IR Quantification of Doripenum in Pharmaceutical dosage form Trade Science Inc.
Dr.V.Niraimathi UV Spectrophotometric Methods for the estimation of Chlorthalidone in Bulk and Oral Dosage form Indo American Journal of Pharmaceutical Research Vol 3Issue 9, 2013
Dr.V.Niraimathi Spectrofluorimetric quantification of Isoxsuprin Hydrochloride in Bulk and Oral dosage form IJPT, 2013, Vol 5 Issue No 1. P 5503 – 5509
Dr.V.Niraimathi IR Quantification of Isoxsuprine Hydrochloride in Bulk and Oral Dosage form Int. J. Pharm. Sci.Rev. Res, 20(2), 2013, P 170 – 172
Dr.V.Niraimathi Forced Oxidative Degradation study of Doripenem by UV Spectrophotometric method. IJPPS, Vol 5, Suppl, 2013, P. 430 – 431
Dr.V.Niraimathi Forced Hydrolytic Degradation Study of Doripenem by UV Spectrophotometric method Int. J. Pharm. Sci.Rev. Res, 20(2), 2013, P 155 – 157
Dr.V.Niraimathi Quantitative Nuclear Magnetic Resonance Spectroscopic Analysis of Valsartan in Bulk and Solid Oral Dosage form Asian Journal Of Chemistry, Vol 25, No 8, 2013, 4267 – 4270
Dr.V.Niraimathi Visible Spectrophotometric Methods for the estimation of Cinitapride and Omeprazole in Bulk and Oral Dosage Form. International Standard Serial Number
Dr.V.Niraimathi Forced Degradation study of Alverine citrate in acid by UV  Spectrophotometry method Indo American Journal of Pharmaceutical Research, Vol 3 , Issue 11, 2013
Dr.V.Niraimathi Forced Degradation study of Cefuroxime Axetil in Alkali by UV  Spectrophotometry method Indo American Journal of Pharmaceutical Research, Vol 3 , Issue 11, 2013
 
Dr.V.Niraimathi Visible SpectrophotometricMethods for the estimation of Cinitapride and Omeprazole in Bulk and Oral and Oral Dosage Form International Standard Serial Number
Dr.P.G. Sunitha Development and Validation of Spectrophotometric methods for the determination of Efavirenz in Tablets Research Journal of Pharmaceutical, Biological & Chemical Sciences- 2013, , Vol 4, Issue 1, 229- 233
Dr.P.G. Sunitha FTIR Spectroscopic Method for Quantitative Analysis of Etoricoxib in Tablets Research Journal of Pharmaceutical, Biological & Chemical Sciences, Vol 4, Issue 3, 252- 255
Dr.P.G. Sunitha Charge Transfer complex for the estimation of Etoricoxib in Tablets Journal of Drug delivery and Therapeutics, 2013, 3(3), 98 -99
Dr.P.G. Sunitha Development and Validation of Spectrophotometric Methods for Quantification of Etoricoxib in Tablets. International Journal of Pharma Research, 2013, 57 – 59
 
Dr. M.Sathish
Antimicrobial activity of extracts and isolated compounds of Clerodendrum phlomidis IJPPS, Vol 5, Issue issue 4 , 2013, 362 – 366
 
Dr. M.Sathish
In vitro antioxidant activity of extracts and stigmasterol from leaves of Clerodendrum inerme Linn Research Journal of Pharmaceutical, Biological & Chemical Sciences, Vol 4, Issue 4, 1411 – 1418
Dr. N Deattu Formulation and Evaluation of Midazolam Mucoadhesive Buccal Patches for Acute Seizures International Journal of Pharma Research, 2013,
Dr. N Deattu Efficacy of 23.4% Hypertonic saline in the Management of Intracranial Hypertension International Journal of Pharma Research , 2013
Dr.S.Daisy Chellakumari Formulation, Characterisation and optimization of MTX loaded Sodium alginate Chitosan Nanoparticles using 32 factorial design. Indian Journal of research in Pharmacy and Biotechnology Vol- I, Issue 6, 2013.
Dr.S.Daisy Chellakumari Preparation, Characterisation and Anti-inflammatory activity of Chitosan Stabilised Silver Nanoparticles. Research J.Pharma. Dosage forms and Tech,5(3); 161 – 167, 2013.
Dr.S.Daisy Chellakumari Formulation and Evaluation of Three layer controlled release matrix tablets of Tolterodine-L-Tartrate. Journal of Pharma research 2(4),5-8,2013.
Dr. N. Jayshree Pancreatic Lipase Inhibitory activity of various extracts of aerial parts of Lagenaria siceraria International Journal of Pharmacy and Integrated Life Sciences, VI- (14)PG (140- 148)
Dr. N. Jayshree Antitubercular activity on leaves and roots of Sida rhombifolia Int. J. Pharm. Sci.Rev. Res, 20(2), 2013, p. 135 - 137
Dr. N. Jayshree Development and Standardisation and Evalution of Polyherbal Syrup Int. J. Pharm. Sci.Rev. Res, 20(2), 2013, P. 149 - 154
Dr. N.Jayshree Pharmacognosy, Phytochemical and in vitro evaluation of SPF for the leaves and flowers of Delonix regia and leaves of Samanea suman Journal of Pharmacognosy and Herbal Formulation Vol 3: 13,2013, p. 23- 29
Dr. N. Jayshree Pharmacogostical and Phytochemical investigation of aerial parts of Lagenaria siceraria  Mol Standley International Journal of Pharmaceutical Research Scholars V -2, 1- 2, 2013
Dr. N. Jayshree Formulation and Evaluation of  Sunscreen cream containing flower extract of Delonix regia International Journal of Pharmacy & Integrative Life Sciences, Vol (16) PG 111 - 129
Dr. N. Jayshree Pharmacological Evaluation of a Polyherbal Formulation for the Management of Benign Prostatic Hyperplasia International Journal of Current Pharmaceutical Research, Vol 5 issue 1, 2013
Dr. N. Jayshree Anti obesity potential of the ethanolic extract and the isolated compound (isoquercitin) of aerial parts of Lagenaria siceraria (Mol) Standley in Hypercholesterolemic Zebra fish. International Journal of Universal Pharmacy & Bioallied Sciences 2(4) 2013, 202- 216
Dr. R. Radha Development standardization and accelerated stability studies of a polyherbal formulation Vol 1 issue 2: 2013 p.29 -51
Dr. R. Radha Cytotoxic Evaluation and In vitro Hepatoprotective effect on Aerial Parts of Acalypha Fruticosa Forssk Journal of Pharmacognosy and Herbal Formulation, Vol 3: 13. 2013. P 16-20
Dr. R. Radha In Vitro Antioxidant and Antiarthritic activity of Polyherbal Formulation Journal of Pharmacognosy and Herbal Formulation, Journal of Pharmacognosy and Herbal Formulation, Vol 3: 13. 2013. P.11 -16
Dr. R. Radha Preliminary Phytochemical screening and antimicrobial activity of leaves of Trichodesma indicum Linn International Journal of Frontiers in Science and Technology, Vol 1, Issue 1, 2013
Dr. Vijaya bharathi Hypolipidemic activity on ethanolic extract of leaves of Ziziphus oenoplia (L) Mill Gard. International Journal of Pharmaceutical & Biological Archives 2013; 4(1): 136- 141
Dr. Vijaya bharathi Preliminary Phytochemical Screening and Heavy metal Analysis of Leaf extracts of Ziziphus oenoplia (L) Mill Gard International Journal of Pharmaceutical Sciences and Drug Research, 2013, 5(1) 38 - 40
Dr. R. Vadivu Standardization and evaluation of hepatoprotective activity of Polyherbal capsule Int. J. Pharm. Sci.Rev. Res,21(1) 2013, p 93 - 99
Dr. R. Vadivu Formulation and Standardization of Polyherbal Antiasthmatic capsule and its Pharmacological activity Journal of Pharmacognosy and Herbal Formulation, Vol 3: 13. 2013. P 1- 9
Dr. P.Muthusamy Antidiabetic and hypolipidemic effect of ethanol extract of leaves of Swietenia macrophylla King in normal and streptoazotocin induced diabetic rats. International Journal of Pharmacy & Integrative Life Sciences, VI (15), PG (162 -163)
Dr. A.Jerad Suresh Synthesis, preclinical evaluation and antidepressant activity of 5-substituted phenyl-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole-1-carbothioamides. Experimental and Clinical Sciences . 2014. Vol 33
Dr. A.Jerad Suresh Heteroaryl chalcones: Mini review about their therapeutic voyage Biomedicine & Preventive Nutrition Volume 4, Issue 3, July–September 2014, Pages 451–458
Dr. A.Jerad Suresh Plant Secondary Metabolites- Potent Inhibitors of Monoamine Oxidase Isoforms Central Nervous System Agents in Medicinal Chemistry. Volume 14, Number 1. 2014
Dr. A.Jerad Suresh Synthesis, in silico preclinical evaluation, antidepressant potential of 5-substituted phenyl-3-(thiophen-2-yl)-4,5-dihydro-1h-pyrazole-1-carboxamides Biomedicine & Aging Pathology Volume 4, Issue 4, October–December 2014, Pages 327–333
Dr. A.Jerad Suresh Proposed interaction of some novel antidepressant pyrazolines against monoamine oxidase isoforms. Molecular docking studies and PASS assisted in silico approach. Biomedicine & Aging Pathology Volume 4, Issue 4, October–December 2014, Pages 297–301
 
Dr. PG Sunitha Validated First order derivative spectrophotometry for simultaneous determination of emtricitabine and Tenofovir Disoproxil Fumarate in Pharmaceutical dosage form. Journal of Drug delivery and Therapeutics. 2014, 4 (2) 9 -11
Dr. PG Sunitha Validated First order derivative spectrophotometry for simultaneous determination of Febuxostat and Diclofenac in Pharmaceutical Dosage form Research journal of Pharmaceutical and Biological Sciences. May –June 5(3) 2014. Page 1675 – 1681.
Dr. PG Sunitha FTIR Spectroscopic Method for Quantitative Analysis of Gliclazide in Tablets World Journal of Pharmacy & pharmaceutical Sciences Journal of Drug delivery and Therapeutics. 2014, 4(3) 145 -146.
Dr. PG Sunitha Validated RP HPLC and HPTLC methods for Simultaneous estimation of Febuxostat and diclofenac sodium in Pharmacetical dosage form European journal of Chemistry 5 (3) 2014. 545 -549
 
Dr. PG Sunitha Visible Spectrophotometric Method for the estimation of gliclazide in Tablets Int. j.Drug Dev & Res., April – June  2014, 6 (2) 280 – 285
 
Dr. PG Sunitha Development and validation of spectrophotometric Methods for Quantification of Gliclazide in Tablets Research journal of Pharmaceutical and Biological Sciences. July – August 2014. 5(4) 323 - 327
Dr. PG Sunitha Validated HPTLC Method for the Simultaneous determination of Phenylephrine and Levocetrizine in Drug formulation International Journal of Pharma Research Volume 5 : 2 July December 2014
Dr. PG Sunitha Validated RP HPLC for Simultaneous estimation of Phenylephrine and Levocetrizine in Pharmaceutical Dosage form Vol 3, Issue 11, 2014; 1326 - 1334
Dr. PG Sunitha Development of Spectrophotometric method for the simultaneous estimation of Phenylephrine and Levocetrizine in Pharmaceutical Int. j.Drug Dev & Res., October – November 2014, 6(4) 280 -285
 
Dr. Daisy Chella Kumari Optimization of Methotrexate Containing Alginate-Chitosan Nanoparticle By 3 Factor, 3 Level Box-Behnken Design International Research journal for inventions in Pharmaceutical Sciences. 2014. Vol 2 Issue 1, 38 – 45
Dr. Daisy Chella Kumari Formulation and in vitro Characterisation if Glipizide loaded Muco –adhesive Gelatin Microsphere Int J Innovations Pharm Sci, 3(2), 41 – 52,2014
Dr. R Radha In vitro Hyperpigmentant activity on the bark of Dalbergia sissoo Roxb. Am. J. Pharm Health Res 2014;2(3). 94- 98
Dr. P. Muthusamy In Vitro Anti-Oxidant and Anti-Arthritic Activity of Polyherbal Formulation (Capsules) Am. J. Pharm Health Res 2014;2(3). 66 - 72
Dr R Vadivu Memory strengthening activity on seeds of Abelmoschus moschatus International journal of research in pharmacy and chemistry IJRPC.  2014, 4(2),346 - 350
Dr. R  VijayaBharathi Pharmacognostical and phytochemical studies on leaves of vitex leucoxylon linn International Journal of Research in Pharmaceutical and Nano Sciences. 3(3), 2014, 229 - 234.
Dr. N Jayshree Anti-Pancreatic lipase activity of leaves of operculina turpethum International Journal of Institutional Pharmacy and life sciences4(2): March-April 2014
Dr. N Jayshree Hepatoprotective Activity of the berries of Vitex Agnus-Castus International Journal of innovations in pharmaceutical sciences
Dr. N Jayshree Phytochemical Screening and In vitro Hepatoprotective Activity on the Berries of vitex Agnus-Castus International Journal of Pharmacy and Industrial Research
Dr. N Jayshree Hypolipidemic potential of leaves of Operculina turpethum International Journal of innovations in pharmaceutical sciences
Dr. N Jayshree Analgesic and Antipyretic Activity of Transdermal Patches containing Solasodine Isolated from solanum surattense International Journal of innovations in pharmaceutical sciences
Dr. R. Priyadarsini Predicting of Binding energies/ interactions between newly designed anti diabetic molecules and different target of PPAR α, β, γ receptors by molecular docking studies Journal of Pharmacy Research 2014, 8(11), 1653 – 1664
 
Dr. A.Jerad Suresh Development of fluorinated methoxylated chalcones as selective monoamine oxidase-B inhibitors: Synthesis, biochemistry and molecular docking studies Bioorganic Chemistry       Volume 62, October 2015, Pages 22–29.
Dr. A.Jerad Suresh Monoamine Oxidase Inhibitory Action of Chalcones: A Mini Review Central Nervous System Agents in Medicinal Chemistry [2015]
Dr. A.Jerad Suresh Hydrazones as a Privileged Structural Linker in Antitubercular Agents: A Review Drug Targets (Formerly Current Drug Targets - Infectious Disorders)  Volume 15, Number 2 June 2015, pp. 76-88(13).
Dr. A.Jerad Suresh Flavonoids: An Outstanding Structural Core for the Inhibition of Xanthine Oxidase Enzyme Current Enzyme Inhibition. Volume 11, Number 2, August 2015, pp. 108-115(8).
Dr. A.Jerad Suresh Psychomotor Seizure Screening and in vitro Neuroprotection Assay of Hydrazones Derived from 2-Acetyl Thiophene. Central Nervous System Agents in Medicinal Agents) 15(999) · October 2015
Dr. A.Jerad Suresh Development of Fluorinated Thienylchalcones as Monoamine Oxidase-B Inhibitors: Design, Synthesis, Biological Evaluation and Molecular Docking Studies Letters in Organic Chemistry 09/2015; 12(999):1-1.
 
Dr. A.Jerad Suresh Development of fluorinated methoxylated chalcones as selective monoamine oxidase-B inhibitors: Synthesis, biochemistry and molecular docking studies Bioorganic Chemistry 62:22-29 · July 2015
 
Dr. A.Jerad Suresh
Molecular Hybridization and Preclinical Evaluation of Imines From Para-substituted 4-phenyl 2-amino Thiazole Incorporated with Isatin Analogues as Antitubercular Agents

 

Anti-Infective Agents 05/2015 13(1).

Dr. PG Sunitha Validated HPTLC Method for the Simultaneous determination of  emtricitabine and Tenofovir in Drug formulation International Journal of Pharmaceutical Science and Research. Vol 6(6): 2418 -2422. 2015
 
Dr. PG Sunitha Simultaneous quantification of  emtricitabine and Tenofovir  Disoproxil Fumarate in spiked human plasma by HPLC World Journal of Pharmacy & pharmaceutical Sciences. Vol 4, Issue 11, 1182 – 1187. 2015
Dr. M.Sathish In vitro antioxidant and cytotoxic activity of isolated compounds on roots of Clerodendrum phlomidis linn Asian Journal of Pharmaceutical and Clinical Research. Vol 8, issue 1, 196 - 201
Dr. R Radha A review on Hybanthus enneaspermus Research journal of Pharmacognosy and Phytochemistry. 7(4),October – December, 2015, 245 – 249
Dr. R Radha Pharmacognostical and Phytochemical studies on Heartwood of Caesalpinia sappan Linn. International journal of Pharmacy and Integrated Life Sciences. Vol 4 (1) December 2015
Dr. R Radha Pharmacognosy of Azima Tetracantha Lam a Review International Journal of Pharma Research. December2015, Vol3 Issue 12
Dr. R Radha An Overview: Citrus maxima Journal of Phytopharmacology 2015; 4(5) 263 –266
Dr. P. Muthusamy A review on Adansonia digitata Journal of Pharmacognosy and Phytochemistry. 2015; 4(4) 12 – 16
Dr. P. Muthusamy Pharmacognosy studies on seeds of Adansonia digitata Linn International Journal of Pharmacy and Integrated Life Sciences. V-3 (15) PG ( 1 – 13), 2015
Dr. P. Muthusamy Evaluation of Anti – arthritic potential of Adansonia digitata extract. International Journal of Multidisciplinary Research and development Vol 2 Issue 4, 548 – 554, 2015
Dr. P. Muthusamy A review on Adansonia digitata – potential herb Research Journal of Pharmacognosy and Phytochemistry 7(1) January – March, 2015, 57 -60
Dr. P. Muthusamy A Overview – royal Poinciana. Research journal of Pharmacognosy and Phytochemistry 7 (4) October – December, 2015, 232 – 238.
Dr.R Vadivu Preliminary Phyto Chemistry and in vitro cytotoxic activity of the leaves of Asparagus racemosus willd International journal of Pharma Sciences and Research.Vol 6, No 4, Apr 2015
Dr. R  Vadivu Pharmacognostical Standardization of leaves of Asparagus racemosus wild International Journal of Multidisciplinary Research and development 2015, 2 (1) 332 – 335
Dr. R  Vadivu Evalution of Antimicrobial activity of the Leaves of Ixora coccinia Linn. International journal of Pharmacy and Integrated Life Sciences.  Dec 2015; 4 (1): 50 – 59.
Dr. R  Vadivu A Review on Sterculia foetida Linn Research journal of Pharmacognosy and Phytochemistry 7(4): October – December, 2015, 239 – 244
Dr. R  Vijaya Bharathi A review on Zanthoxylum alatum Roxb Research journal of Pharmacognosy and Phytochemistry. 7(4), October – December, 2015, 223 – 226
Dr. R  Vijaya Bharathi Vigna unguiculata -  An Overview Review Research journal of Pharmacognosy and Phytochemistry..  7(4), October – December, 2015,219- 222
Mrs. R Indumathy Cytotoxic potential of various extracts of lepidium sativum (Linn) An in–vitro Evaluation International Journal of Pharmacology and Pharmaceutical Sciences.2015 Vol 2(4):
Dr. A.Jerad Suresh Pharmacophore Modeling, 3D-QSAR and Molecular Docking of Furanochalcones as Inhibitors of Monoamine Oxidase-B Central Nervous System Agents) 03/2015
Dr. N. Jayshree Erythrina stricta Roxb: A Phytopharmacological Review International Journal of Multidisciplinary Research and development. Vol: 2, 2015, Issue 5 : 98 – 101
 
Dr. R Radha Pharmacognostical Standardization of roots of Curcuma angustifolia Roxb International Journal of Multidisciplinary Research and development. Vol 2 Issue 4: 142 – 144. April 2015
Dr R Vadivu A review of Sida Spinosa Linn American Journal of Pharmtech Research. Am.J.Pharm Tech Res. 2015; 5(5). 131 -140
 
 
 
           11. HIGHLIGHTS OF THE YEAR 2016
Our M.Pharm students actively participated in the CPE Program on “Recent Innovations in Nanoparticulate Drug Delivery System for targeting cancer cells” conducted by Adhiparasakthi College of Pharmacy, Melmaruvathur, Chennai and Co-sponsored by The Tamilnadu Dr.M.G.R Medical University on 30.01.2016.
Our Students participated at the 55th National Pharmacy week celebration held at Sri Ramachandra University, Porur on 21st & 22nd Nov 2016 and won the following Prizes.
 
CHESS                                                                QUIZ
I Prize – R.Balakumar (B.Pharm)       I Prize - R.Narayanaswamy (M.Pharm)
II Prize – B.Lokesh Sharan (B.Pharm)               S.Dhiraj Kumar (B.Pharm)
                                                                            T.S.Karthik (B.Pharm)
 
CARROM
                                                             II Prize - M.Karthick (M.Pharm)
II Prize – K.Prabhu Narayanan(B.Pharm)                    S.Shanmuga Priya(M.Pharm)                                                                     R.Karthikeyan(B.Pharm)
Our Students participated at the 55th National Pharmacy week celebration conducted in Silver Jubilee auditorium of The Tamilnadu Dr. M.G.R Medical University on November 25 th 2016 and  awarded scholarship sponsored by Pharmaceutical Sciences Welfare trust  for their M.Pharm ongoing Projects.
1) I Prize –   V.Shiva Kumar (Dept of Pharm Chemistry)
2) II Prize -   A.Menaka (Dept of Pharm Chemistry)    
  Percial (Dept of Pharmacology)
3) III Prize – M.Madhuraj (Dept of Pharm Chemistry)
 S.Shanmuga Priya (Dept of Pharmacognosy)
                     
Ms. Surya. P.R, M.Pharm, Ph.D., participated in Poster presentation in “NATIONAL SEMINAR ON RECENT ADVANCES IN HIV/AIDS DRUG DISCOVERY AND DEVELOPMENT” on December 27 & 28, 2016 organized by KALASALINGAM UNIVERSITY in association with Antiviral Research Society and won the Best Poster Presentation award at National level.
                                                                                                                        

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